Bromelain Sinus Ease

. . . synergistically works to reduce sinus pain and the body's natural inflammatory response*

Doctor Formulated

• Contains Bromelain, Quercetin and Vitamin C

• Bromelain helps reduce swelling and inflammatory  response to sinuses by increasing the body's ability to break down fibrin1*

• Bromelain thins mucus allowing sinuses to drain more easily2*

• Vitamin C has mild antihistamine activity3*

• Vitamin C, when given with bioflavonoids like quercetin, has reduced the inflammatory response4*

• Quercetin, a potent plant bioflavonoid, eases painful inflammatory response5*

Benefits of Sinus Ease

        Sinus cavities are lined with delicate mucous membranes, which act as filters for your respiratory system. When attacked by allergies, pollutants, viruses or bacteria, they respond by becoming swollen and inflamed.

        Bromelain helps inhibit the formation of prostaglandins that trigger the inflammatory response.6* It also makes mucus less thick, allowing mucus to drain more easily.2* Fibrin is a protein that concentrates in areas of inflammation, causing painful swelling.* Bromelain decreases fibrin deposits, preventing damaging buildup in the sinuses and elsewhere.1*

        Human trials have shown that by removing fibrin from areas of inflammation, bromelain lessens swelling.1* Inflamed sinuses respond well to bromelain.* Double-blinded trials show that the inflammatory response is better reduced by bromelain than by placebo.7,8,9,10* In all cases, a majority of people responded well to bromelain supplements.*

        Quercetin reduces the inflamma­tory response by inhibiting release of pro-inflammatory leukotrienes, which are similar to prostaglandins.11* Leukotrienes are one of the most potent pro-inflammatory substances produced by our bodies—over 3,000 times more powerful than prostaglandins.* Quercetin also protects white blood cells which, when damaged, release pro-inflammatory histamine.5* Quercetin may also have anti-viral activity.4*

        Bioflavonoids may help decrease swelling by reducing capillary fragility and permeability.* In human studies, the inflammatory response was decreased when bioflavonoids were given in combination with vitamin C, an outcome con­firmed in double-blinded research.4,12*

        Vitamin C has mild antihistamine activity.3,13* As a possible consequence, some studies have reported that vitamin C is useful in reducing painful, swollen nasal passages.14,15,16* The effectiveness of vitamin C in producing anti­histamine effects is still debated, however, because a controlled trial was unable to show consistent effects.17* Doses up to 2 grams per day have been used by researchers.13* It may be diffi­cult to show these effects in research trials because vitamin C appears to help only some people without affecting others.18*

Ingredient Highlights

        Bromelain is a protein-digesting enzyme found in pineapple. Nature’s Life uses high activity bromelain—each 3 capsules provides 2,880 GDU (4,320 MCU). Bromelain should be taken on an empty stomach. If taken with food, bromelain’s activity may be lessened.* When taken without food, bromelain will be absorbed into the bloodstream and will be available to help reduce the inflammatory response.* Bromelain is safe; many studies have reported no side effects, except a mild diarrhea at very high doses.*

        Quercetin is a safe, potent bioflavonoid found in many plants.* Nature’s Life uses quercetin from the pod of a tropical tree of the Dimorphandra species. Quercetin is virtually non-toxic but may cause mild diarrhea in sensitive people.

                Our Vitamin C is pure, hypoallergenic calcium ascorbate. Calcium is a very effective buffer. When combined with ascorbic acid to form calcium ascorbate, it is easier on the stomach. People who cannot use ascorbic acid because of its acidity, can usually tolerate calcium ascorbate very well.

References

1. Prac­titioner 1969;203:206.

2. Exper Med Surg 1962;20:228-48.

3. J Am Coll Nutr 1992;11:172-6.

4. Med Times 1960;88:313-6.

5. Arch Allergy Applied Immunol 1985;77:155-7.

6. Med Hypoth 1980;6:99-104.

7. EENT Monthly 1966;45:96-8.

8. EENT Monthly 1967;46:361-5.

9. Headache 1967;7:13-7.

10. EENT Monthly 1967;46:1281-8.

11. Prog Clin Biol Res 1986;213:231-42.

12. Med Times 1962;529-32.

13. J Am Diet Assoc 1992;92(8):988-9.

14. Am J Dig Dis 1945;12:281.

15. J Allergy Clin Immunol 1973;51:218.

16. Science 1942;96;497.

17. J Allergy Clin Immunol 1982;69:484-8.

18. NZ Med J 1986;99:163 [abstr].